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|Title:||Diversity-oriented optical imaging probe development|
|Citation:||Lee, J.-S., Vendrell, M., Chang, Y.-T. (2011-12). Diversity-oriented optical imaging probe development. Current Opinion in Chemical Biology 15 (6) : 761-767. ScholarBank@NUS Repository. https://doi.org/10.1016/j.cbpa.2011.10.007|
|Abstract:||The development of optical probes is receiving considerable attention due to their rising adaptation in diagnostics and medical imaging. Diversity-oriented approaches make use of combinatorial chemistry and high-throughput screenings to enrich the spectral and structural variety of these probes and effectively identify those with specific properties (e.g. molecular affinity, cellular selectivity, high photostability, and sensitivity). Herein we review recent examples in which diversity-driven strategies have assisted the discovery of new molecular imaging probes. © 2011 Elsevier Ltd.|
|Source Title:||Current Opinion in Chemical Biology|
|Appears in Collections:||Staff Publications|
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