Electrochemical detection of polynuclear aromatic hydrocarbons following reversed-phase gradient high-performance liquid chromatography using a large-volume wall-jet detector

Abstract

Electrochemical detection is rarely used in conjunction with gradient high-performance liquid chromatography. The problem is the changing eluent composition and electrolyte concentration during a gradient run which greatly affects the performance of electrochemical detectors. However, by the use of a large-volume wall-jet detector a means of obviating the problem is afforded. This paper reports on an application to the analysis of polynuclear aromatic hydrocarbons.