Synthesis and anti-cancer activities of a pair of enantiomeric gold(I) complexes containing sulfanyl-substituted P-stereogenic phosphines

Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0957-4166(99)00106-8

Title:	Synthesis and anti-cancer activities of a pair of enantiomeric gold(I) complexes containing sulfanyl-substituted P-stereogenic phosphines
Authors:	Song, Y. Vittal, J.J. Srinivasan, N. Chan, S.-H. Leung, P.-H.
Issue Date:	23-Apr-1999
Citation:	Song, Y., Vittal, J.J., Srinivasan, N., Chan, S.-H., Leung, P.-H. (1999-04-23). Synthesis and anti-cancer activities of a pair of enantiomeric gold(I) complexes containing sulfanyl-substituted P-stereogenic phosphines. Tetrahedron Asymmetry 10 (8) : 1433-1436. ScholarBank@NUS Repository. https://doi.org/10.1016/S0957-4166(99)00106-8
Abstract:	A pair of enantiomeric gold(I) complexes containing enantiomerically pure 2,3-dimethyl-7-phenyl-5-(phenylsulfanyl)-7-(R/S)- phosphabicyclo[2.2.1]hept-2-ene has been prepared and in vitro cytotoxicity tests showed that both the enantiomers are relatively nontoxic against healthy lymphocytes, but are highly potent against suspension and monolayer human tumor cell lines.
Source Title:	Tetrahedron Asymmetry
URI:	http://scholarbank.nus.edu.sg/handle/10635/77125
ISSN:	09574166
DOI:	10.1016/S0957-4166(99)00106-8
Appears in Collections:	Staff Publications

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