Please use this identifier to cite or link to this item: https://doi.org/10.1002/marc.200600855
Title: Single base pair mismatch detection using cationic conjugated polymers through fluorescence resonance energy transfer
Authors: Tian, N.
Tang, Y.
Xu, Q.-H. 
Wang, S.
Keywords: Biological applications of polymers
Biosensors
Fluorescence
Fluorescence resonance energy transfer
Single nucleotide polymorphism
Water-soluble conjugated polymers
Issue Date: 16-Mar-2007
Citation: Tian, N., Tang, Y., Xu, Q.-H., Wang, S. (2007-03-16). Single base pair mismatch detection using cationic conjugated polymers through fluorescence resonance energy transfer. Macromolecular Rapid Communications 28 (6) : 729-732. ScholarBank@NUS Repository. https://doi.org/10.1002/marc.200600855
Abstract: A simple method using water-soluble conjugated polymers and a DNA intercalator has been proposed for single base pair mismatch detection with enhanced detection efficiency. Fluo- rescence resonance energy transfer (FRET) was used as an indicator for unwinding of dsDNA due to base pair mismatch at elevated temperatures. The optical amplification effect of the CPs helps to achieve enhanced detection efficiency. © 2007 WILEY-VCH Verlag GmbH & Co. KGaA.
Source Title: Macromolecular Rapid Communications
URI: http://scholarbank.nus.edu.sg/handle/10635/76981
ISSN: 10221336
DOI: 10.1002/marc.200600855
Appears in Collections:Staff Publications

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