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|Title:||Selective human serum albumin sensor from the screening of a fluorescent rosamine library|
|Source:||Ahn, Y.-H., Lee, J.-S., Chang, Y.-T. (2008-05). Selective human serum albumin sensor from the screening of a fluorescent rosamine library. Journal of Combinatorial Chemistry 10 (3) : 376-380. ScholarBank@NUS Repository. https://doi.org/10.1021/cc800017h|
|Abstract:||A fluorescent dye library approach for the development of a bioanalyte sensor was sought. The screening of a rosamine dye library against diverse macromolecules led to the discovery of a highly sensitive human serum albumin binder, G13, with ∼36-fold fluorescence intensity change. G13 showed a highly selective response to HSA over other macromolecules including albumins from other species. The potential use of G13 for the detection of HSA in biofluids is described. © 2008 American Chemical Society.|
|Source Title:||Journal of Combinatorial Chemistry|
|Appears in Collections:||Staff Publications|
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