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|Title:||Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [i]-condensed purines|
|Authors:||Fu, H. |
|Source:||Fu, H., Tan, M.K.C., Lam, Y. (2007-09). Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [i]-condensed purines. Journal of Combinatorial Chemistry 9 (5) : 804-810. ScholarBank@NUS Repository. https://doi.org/10.1021/cc7000919|
|Abstract:||A highly regioselective and traceless solid-phase route to 1,7,8-trisubstituted purines has been developed. This methodology could be extended to the preparation of 8-azapurines and [i]-condensed purines. A representative set of 17 purines, azapurines, and [i]-condensed purines was synthesized. This paper also describes a mild method to prepare the p-benzyloxybenzylamine (BOBA) resin. © 2007 American Chemical Society.|
|Source Title:||Journal of Combinatorial Chemistry|
|Appears in Collections:||Staff Publications|
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