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|Title:||Rapid synthesis, screening, and identification of xanthone- And xanthene-based fluorophores using click chemistry|
|Citation:||Li, J., Hu, M., Yao, S.Q. (2009-07-16). Rapid synthesis, screening, and identification of xanthone- And xanthene-based fluorophores using click chemistry. Organic Letters 11 (14) : 3008-3011. ScholarBank@NUS Repository. https://doi.org/10.1021/ol9010344|
|Abstract:||A panel of new fluorophores with emission wavelengths from blue to yellow regions using the Cu(l)-catalyzed 1,3-dipolar cycloaddition reaction of alkyne-functionalized xanthones and xanthenes with various azides have been synthesized. Screening of the "click" products led to the identification of "hit" fluorophores which showed a fluorescence increase upon triazole formation. These novel "click" fluorophores could potentially be used for bioconjugation and bioimaging purposes. © 2009 American Chemical Society.|
|Source Title:||Organic Letters|
|Appears in Collections:||Staff Publications|
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