Please use this identifier to cite or link to this item: https://doi.org/10.1021/ol9010344
Title: Rapid synthesis, screening, and identification of xanthone- And xanthene-based fluorophores using click chemistry
Authors: Li, J.
Hu, M.
Yao, S.Q. 
Issue Date: 16-Jul-2009
Citation: Li, J., Hu, M., Yao, S.Q. (2009-07-16). Rapid synthesis, screening, and identification of xanthone- And xanthene-based fluorophores using click chemistry. Organic Letters 11 (14) : 3008-3011. ScholarBank@NUS Repository. https://doi.org/10.1021/ol9010344
Abstract: A panel of new fluorophores with emission wavelengths from blue to yellow regions using the Cu(l)-catalyzed 1,3-dipolar cycloaddition reaction of alkyne-functionalized xanthones and xanthenes with various azides have been synthesized. Screening of the "click" products led to the identification of "hit" fluorophores which showed a fluorescence increase upon triazole formation. These novel "click" fluorophores could potentially be used for bioconjugation and bioimaging purposes. © 2009 American Chemical Society.
Source Title: Organic Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/76858
ISSN: 15237060
DOI: 10.1021/ol9010344
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