Please use this identifier to cite or link to this item: https://doi.org/10.1002/pmic.201000278
Title: Proteomic analysis of human gastric juice: A shotgun approach
Authors: Liang, C.R.M.Y. 
Tan, S. 
Tan, H.T. 
Lin, Q. 
Lim, T.K. 
Liu, Y. 
Yeoh, K.G.
So, J.
Chung, M.C.M.
Keywords: Biomedicine
Gastric juice
Gastritis
Shotgun proteomics
Issue Date: Nov-2010
Citation: Liang, C.R.M.Y., Tan, S., Tan, H.T., Lin, Q., Lim, T.K., Liu, Y., Yeoh, K.G., So, J., Chung, M.C.M. (2010-11). Proteomic analysis of human gastric juice: A shotgun approach. Proteomics 10 (21) : 3928-3931. ScholarBank@NUS Repository. https://doi.org/10.1002/pmic.201000278
Abstract: Gastric juice is the most proximal fluid surrounding the stomach tissue. The analysis of gastric juice protein contents will thus be able to accurately reflect the pathophysiology of the stomach. This biological fluid is also a potential reservoir of secreted biomarkers in higher concentration as compared to the serum. Unlike the rest of the gastrointestinal fluids, there were very few studies reported on gastric juice proteome. To date, the proteins that routinely populate this biofluid are largely unknown. This is partly due to the technical difficulties in processing a sample that contains a collection of other gastrointestinal fluids, especially saliva. In this study, we attempt to profile the protein components of the gastric fluids from chronic gastritis patients using a direct shotgun proteomics approach. These data represent the first report of the proteome of human gastric juice with gastritis background. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Proteomics
URI: http://scholarbank.nus.edu.sg/handle/10635/76836
ISSN: 16159853
DOI: 10.1002/pmic.201000278
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