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https://doi.org/10.1002/1097-4636(200101)54:1<59
DC Field | Value | |
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dc.title | Preparation and characterization of chitin beads as a wound dressing precursor | |
dc.contributor.author | Muhammad Yusof, N.L.B. | |
dc.contributor.author | Lim, L.Y. | |
dc.contributor.author | Khor, E. | |
dc.date.accessioned | 2014-06-23T05:47:16Z | |
dc.date.available | 2014-06-23T05:47:16Z | |
dc.date.issued | 2001-01 | |
dc.identifier.citation | Muhammad Yusof, N.L.B.,Lim, L.Y.,Khor, E. (2001-01). Preparation and characterization of chitin beads as a wound dressing precursor. Journal of Biomedical Materials Research 54 (1) : 59-68. ScholarBank@NUS Repository. <a href="https://doi.org/10.1002/1097-4636(200101)54:1<59" target="_blank">https://doi.org/10.1002/1097-4636(200101)54:1<59</a> | |
dc.identifier.issn | 00219304 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/76804 | |
dc.description.abstract | Chitin was dissolved in N, N-dimethylacetamide/5% lithium chloride (DMAc/5%LiCl) to form a 0.5% chitin solution. Chitin beads were formed by dropping the 0.5% chitin solution into a nonsolvent coagulant, ethanol. The beads were left in ethanol for 24 h to permit hardening, consolidation, and removal of residual DMAc/5%LiCl solvent in order to give spherical chitin beads uniform size distribution. The ethanol-gelled chitin beads had an average diameter of 535 μm. The chitin beads were subsequently activated in 50% (w/v) NaOH solution and reacted with 1.9 M monochloroacetic acid/2-propanol solution to introduce a carboxymethylated surface layer to the chitin beads. The bilayer character of the surface-carboxymethylated chitin (SCM-chitin) beads was verified by Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA), and confocal microscopy. The bilayered SCM-chitin beads were found to absorb up to 95 times their dry weight of water. These SCM-chitin beads have potential as a component of wound dressings. (C) 2000 John Wiley and Sons, Inc. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/1097-4636(200101)54:1<59 | |
dc.source | Scopus | |
dc.subject | Carboxymethyl chitin | |
dc.subject | Chitin | |
dc.subject | Chitin beads | |
dc.subject | Cytotoxicity | |
dc.subject | Water uptake | |
dc.type | Article | |
dc.contributor.department | CHEMISTRY | |
dc.contributor.department | PHARMACY | |
dc.description.doi | 10.1002/1097-4636(200101)54:1<59 | |
dc.description.sourcetitle | Journal of Biomedical Materials Research | |
dc.description.volume | 54 | |
dc.description.issue | 1 | |
dc.description.page | 59-68 | |
dc.description.coden | JBMRB | |
dc.identifier.isiut | 000165589000007 | |
Appears in Collections: | Staff Publications |
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