Please use this identifier to cite or link to this item: https://doi.org/10.1021/la063658k
Title: Optimizing biosensing properties on undecylenic acid-functionalized diamond
Authors: Zhong, Y.L.
Chong, K.F.
May, P.W.
Chen, Z.-K.
Loh, K.P. 
Issue Date: 8-May-2007
Citation: Zhong, Y.L., Chong, K.F., May, P.W., Chen, Z.-K., Loh, K.P. (2007-05-08). Optimizing biosensing properties on undecylenic acid-functionalized diamond. Langmuir 23 (10) : 5824-5830. ScholarBank@NUS Repository. https://doi.org/10.1021/la063658k
Abstract: The optimization of biosensing efficiency on a diamond platform depends on the successful coupling of biomolecules on the surface, and also on effective signal transduction in the biorecognition events. In terms of biofunctionalization of diamond surfaces, surface electrochemical studies of diamond modified with undecylenic acid (UA), with and without headgroup protection, were performed. The direct photochemical coupling method employing UA was found to impart a higher density of carboxylic acid groups on the diamond surface compared to that using trifluoroethyl undecenoate (TFEU) as the protecting group during the coupling process. Non-faradic impedimetric DNA sensing revealed that lightly doped diamond gives better signal transduction sensitivity compared to highly doped diamond. © 2007 American Chemical Society.
Source Title: Langmuir
URI: http://scholarbank.nus.edu.sg/handle/10635/76694
ISSN: 07437463
DOI: 10.1021/la063658k
Appears in Collections:Staff Publications

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