Please use this identifier to cite or link to this item: https://doi.org/10.1021/ol100816g
Title: One-pot synthesis of amine-substituted aryl sulfides and benzo[ b ]thiophene derivatives
Authors: Duan, Z. 
Ranjit, S.
Liu, X. 
Issue Date: 21-May-2010
Citation: Duan, Z., Ranjit, S., Liu, X. (2010-05-21). One-pot synthesis of amine-substituted aryl sulfides and benzo[ b ]thiophene derivatives. Organic Letters 12 (10) : 2430-2433. ScholarBank@NUS Repository. https://doi.org/10.1021/ol100816g
Abstract: A series of amine-substituted aryl sulfides have been synthesized from nitroaryl halides via a simple one-pot procedure involving metal-free C-S cross-coupling and in situ nitro group reduction. Various nitroaryl halides were reacted with thiols in recyclable poly(ethylene glycol) to afford the amine-substituted aryl sulfides in high yield. Additionally, the cross-coupling reactions of nitro- and aldehyde-substituted aryl halides with benzyl thiols under the same reaction conditions were demonstrated to afford benzothiazole and phenylbenzo[b]thiophene derivatives. © 2010 American Chemical Society.
Source Title: Organic Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/76671
ISSN: 15237060
DOI: 10.1021/ol100816g
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