Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.tetlet.2013.06.030
Title: | Molecular sieve mediated decarboxylative Mannich and aldol reactions of β-ketoacids |
Authors: | Zhong, F. Jiang, C. Yao, W. Xu, L.-W. Lu, Y. |
Keywords: | Aldol reaction Decarboxylation Ketoacids Mannich reaction Molecular sieves |
Issue Date: | 7-Aug-2013 |
Source: | Zhong, F., Jiang, C., Yao, W., Xu, L.-W., Lu, Y. (2013-08-07). Molecular sieve mediated decarboxylative Mannich and aldol reactions of β-ketoacids. Tetrahedron Letters 54 (32) : 4333-4336. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2013.06.030 |
Abstract: | A molecular sieve mediated decarboxylative Mannich reaction of β-ketoacids with sulfonyl imines is reported; this protocol leads to an efficient preparation of synthetically useful β-amino ketones. An analogous molecular sieve promoted decarboxylative aldol reaction between β-ketoacids and isatins is also described, which affords bioactive 3-substituted-3-hydroxy-oxindoles in excellent yields. © 2013 Elsevier Ltd. All rights reserved. |
Source Title: | Tetrahedron Letters |
URI: | http://scholarbank.nus.edu.sg/handle/10635/76589 |
ISSN: | 00404039 |
DOI: | 10.1016/j.tetlet.2013.06.030 |
Appears in Collections: | Staff Publications |
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