Microwave-assisted synthesis of substituted: 2-(benzylthio)imidazo[1,2a] pyrimidin-5-ones

Please use this identifier to cite or link to this item: https://doi.org/10.1021/cc900176x

Title:	Microwave-assisted synthesis of substituted: 2-(benzylthio)imidazo[1,2a] pyrimidin-5-ones
Authors:	Soh, C.H. Lam, Y.
Issue Date:	8-Mar-2010
Citation:	Soh, C.H., Lam, Y. (2010-03-08). Microwave-assisted synthesis of substituted: 2-(benzylthio)imidazo[1,2a] pyrimidin-5-ones. Journal of Combinatorial Chemistry 12 (2) : 286-291. ScholarBank@NUS Repository. https://doi.org/10.1021/cc900176x
Abstract:	A microwave-assisted solid-phase synthesis of 2-(benzylthio)imidazo[1,2a] pyrimidin-5-ones has been developed. Using microwave irradiation, the reaction time was significantly reduced from a few days to 80 min. A representative set of 10 2-(benzylthio)-6,7-substituted-imidazo[1,2a]pyrimidin-5-ones was prepared. These compounds were subsequently N-alkylated and formylated in good yields. © 2010 American Chemical Society.
Source Title:	Journal of Combinatorial Chemistry
URI:	http://scholarbank.nus.edu.sg/handle/10635/76507
ISSN:	15204766
DOI:	10.1021/cc900176x
Appears in Collections:	Staff Publications

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