Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tetlet.2004.09.049
Title: Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent
Authors: Chan, K.-P.
Loh, T.-P. 
Keywords: In(OTf) 3
InCl 3
Prins cyclization
Tetrahydropyran
Issue Date: 1-Nov-2004
Citation: Chan, K.-P., Loh, T.-P. (2004-11-01). Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent. Tetrahedron Letters 45 (45) : 8387-8390. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2004.09.049
Abstract: A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products. A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products. © 2004 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/76440
ISSN: 00404039
DOI: 10.1016/j.tetlet.2004.09.049
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