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|Title:||Highly enantioselective assembly of functionalized tetrahydroquinolines with creation of an all-carbon quaternary center|
|Citation:||Tan, H.R., Ng, H.F., Chang, J., Wang, J. (2012-03-26). Highly enantioselective assembly of functionalized tetrahydroquinolines with creation of an all-carbon quaternary center. Chemistry - A European Journal 18 (13) : 3865-3870. ScholarBank@NUS Repository. https://doi.org/10.1002/chem.201103136|
|Abstract:||A Mannich-Michael combo: An efficient and highly enantioselective cascade process by H-bonding catalysis for the synthesis of functionalized tetrahydroquinolines has been developed. An indane amine-thiourea small molecule has been discovered to catalyze this process in high yields and with good diastereomeric ratios and excellent enantioselectivities (see scheme). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.|
|Source Title:||Chemistry - A European Journal|
|Appears in Collections:||Staff Publications|
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