Please use this identifier to cite or link to this item: https://doi.org/10.1002/chem.201100927
Title: Expeditious assembly of a 2-Amino-4H-chromene skeleton by using an enantioselective Mannich intramolecular ring cyclization-tautomerization cascade sequence
Authors: Ren, Q.
Siau, W.-Y.
Du, Z.
Zhang, K.
Wang, J. 
Keywords: asymmetric catalysis
cascade reaction
chromene
indane
organocatalysis
thiourea
Issue Date: 4-Jul-2011
Citation: Ren, Q., Siau, W.-Y., Du, Z., Zhang, K., Wang, J. (2011-07-04). Expeditious assembly of a 2-Amino-4H-chromene skeleton by using an enantioselective Mannich intramolecular ring cyclization-tautomerization cascade sequence. Chemistry - A European Journal 17 (28) : 7781-7785. ScholarBank@NUS Repository. https://doi.org/10.1002/chem.201100927
Abstract: Easy to assemble! An enantioselective cascade Mannich intramolecular ring cyclization-tautomerization reaction of malononitrile with 2-hydroxyl N-protected α-amido sulfone is described (see scheme), which provides a new route to the synthesis of the privileged scaffold 2-amino-4H-chromene in high yields (up to 94 %) and with good to high enantiomeric excesses (74-89 % ee). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Chemistry - A European Journal
URI: http://scholarbank.nus.edu.sg/handle/10635/76153
ISSN: 09476539
DOI: 10.1002/chem.201100927
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

73
checked on Dec 14, 2018

WEB OF SCIENCETM
Citations

66
checked on Nov 21, 2018

Page view(s)

52
checked on Nov 24, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.