Please use this identifier to cite or link to this item: https://doi.org/10.1002/adsc.201100419
Title: Enantioselective synthesis of chromanones via a tryptophan-derived bifunctional thiourea-catalyzed oxa-Michael-Michael cascade reaction
Authors: Wang, H.
Luo, J.
Han, X.
Lu, Y. 
Keywords: bifunctional catalysts
cascade reactions
chromanones
chromans
tryptophan
Issue Date: Nov-2011
Citation: Wang, H., Luo, J., Han, X., Lu, Y. (2011-11). Enantioselective synthesis of chromanones via a tryptophan-derived bifunctional thiourea-catalyzed oxa-Michael-Michael cascade reaction. Advanced Synthesis and Catalysis 353 (16) : 2971-2975. ScholarBank@NUS Repository. https://doi.org/10.1002/adsc.201100419
Abstract: Tryptophan-derived tertiary amine-thiourea catalysts were shown to promote a cascade oxa-Michael-Michael reaction between ethylene β-keto esters and nitroolefins, resulting in the formation of 3,3-disubstituted 4-chromanones bearing a quaternary center in high diastereoselectivity and enantioselectivity. The chromanone products can be readily converted to biologically important fused and spiro tricyclic chromans. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Advanced Synthesis and Catalysis
URI: http://scholarbank.nus.edu.sg/handle/10635/76109
ISSN: 16154150
DOI: 10.1002/adsc.201100419
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

20
checked on Jul 14, 2018

WEB OF SCIENCETM
Citations

19
checked on Jul 4, 2018

Page view(s)

31
checked on Jun 8, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.