Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tetlet.2013.03.028
Title: Enantioselective direct fluorination and chlorination of cyclic β-ketoesters mediated by phase-transfer catalysts
Authors: Luo, J.
Wu, W.
Xu, L.-W.
Meng, Y.
Lu, Y. 
Keywords: Chlorination
Fluorination
ketoesters
Phase-transfer catalysis (PTC)
Issue Date: 22-May-2013
Citation: Luo, J., Wu, W., Xu, L.-W., Meng, Y., Lu, Y. (2013-05-22). Enantioselective direct fluorination and chlorination of cyclic β-ketoesters mediated by phase-transfer catalysts. Tetrahedron Letters 54 (21) : 2623-2626. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2013.03.028
Abstract: A straightforward and practical method for the direct fluorination and chlorination of various β-ketoesters employing a phase-transfer catalyst is developed. The desired products with fluorine/chlorine-substituted quaternary chiral centers are prepared with good to excellent enantioselectivities. © 2013 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/76100
ISSN: 00404039
DOI: 10.1016/j.tetlet.2013.03.028
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