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|Title:||Enantioselective direct fluorination and chlorination of cyclic β-ketoesters mediated by phase-transfer catalysts|
Phase-transfer catalysis (PTC)
|Citation:||Luo, J., Wu, W., Xu, L.-W., Meng, Y., Lu, Y. (2013-05-22). Enantioselective direct fluorination and chlorination of cyclic β-ketoesters mediated by phase-transfer catalysts. Tetrahedron Letters 54 (21) : 2623-2626. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2013.03.028|
|Abstract:||A straightforward and practical method for the direct fluorination and chlorination of various β-ketoesters employing a phase-transfer catalyst is developed. The desired products with fluorine/chlorine-substituted quaternary chiral centers are prepared with good to excellent enantioselectivities. © 2013 Elsevier Ltd. All rights reserved.|
|Source Title:||Tetrahedron Letters|
|Appears in Collections:||Staff Publications|
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