Please use this identifier to cite or link to this item:
|Title:||Direct asymmetric three-component organocatalytic anti-selective Mannich reactions in a purely aqueous system|
|Source:||Cheng, L., Wu, X., Lu, Y. (2007). Direct asymmetric three-component organocatalytic anti-selective Mannich reactions in a purely aqueous system. Organic and Biomolecular Chemistry 5 (7) : 1018-1020. ScholarBank@NUS Repository. https://doi.org/10.1039/b701579h|
|Abstract:||The direct three-component Mannich reactions of O-benzyl hydroxyacetone with p-anisidine and aromatic or aliphatic aldehydes in the presence of an l-threonine-derived catalyst afforded anti-1,2-amino alcohols in good-to-excellent yields and with enantioselectivities of up to 97%. This study is the first demonstration that direct three-component Mannich reactions can be promoted by a primary amino acid in water. This journal is © The Royal Society of Chemistry.|
|Source Title:||Organic and Biomolecular Chemistry|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 22, 2018
WEB OF SCIENCETM
checked on Jan 17, 2018
checked on Feb 19, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.