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|Title:||Direct asymmetric Michael addition of phthalide derivatives to chalcones|
Quinine thiourea catalyst
|Citation:||Luo, J., Jiang, C., Wang, H., Xu, L.-W., Lu, Y. (2013-09-18). Direct asymmetric Michael addition of phthalide derivatives to chalcones. Tetrahedron Letters 54 (38) : 5261-5265. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2013.07.108|
|Abstract:||The Michael addition of phthalides to chalcones employing a quinidine-derived thiourea catalyst Q-1 has been developed. The reported method led to the synthesis of 3,3-disubstituted phthalide derivatives in excellent yields, with excellent diastereo- and enantioselectivities. © 2013 Elsevier Ltd. All rights reserved.|
|Source Title:||Tetrahedron Letters|
|Appears in Collections:||Staff Publications|
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