Please use this identifier to cite or link to this item:
Title: Cytotoxicity of triorganophosphinegold(I) n-mercaptobenzoates, n = 2, 3 and 4
Authors: De Vos, D.
Smyth, D.R.
Tiekink, E.R.T. 
Issue Date: 2002
Citation: De Vos, D.,Smyth, D.R.,Tiekink, E.R.T. (2002). Cytotoxicity of triorganophosphinegold(I) n-mercaptobenzoates, n = 2, 3 and 4. Metal-Based Drugs 8 (6) : 303-306. ScholarBank@NUS Repository.
Abstract: The results of cytotoxicity trials against a panel of seven human cell lines for a series of triorganophosphinegold(I) 3- and 4-mercaptobenzoates are reported. While the new compounds show moderate to high toxicity, their potencies are inferior to those reported previously for their isomeric 2-mercaptobenzoate derivatives. The results therefore suggest a structure-activity relationship in that the 2-isomeric species are more active, particularly against the non-small cell lung cancer and renal cancer cell lines, results that may indicate some selectivity in their cytotoxic profile.
Source Title: Metal-Based Drugs
ISSN: 07930291
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

checked on Oct 5, 2018

Google ScholarTM


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.