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|Title:||Chiral indane skeleton based thiourea catalyzed highly stereoselective cascade Michael-enolation-cyclization reaction|
|Citation:||Ren, Q., Gao, Y., Wang, J. (2011-07-21). Chiral indane skeleton based thiourea catalyzed highly stereoselective cascade Michael-enolation-cyclization reaction. Organic and Biomolecular Chemistry 9 (14) : 5297-5302. ScholarBank@NUS Repository. https://doi.org/10.1039/c1ob05477e|
|Abstract:||An efficient asymmetric cascade reaction catalyzed by a chiral bifunctional indane amine-thiourea catalyst has been developed. From a broad substrate scope, chiral dihydro-2H-pyran complexes that contained two stereogenic centers were obtained in a one-pot manner in good to excellent yields (72-97%) and high to excellent stereoselectivities (92-97% ee). © The Royal Society of Chemistry 2011.|
|Source Title:||Organic and Biomolecular Chemistry|
|Appears in Collections:||Staff Publications|
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