Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/75688
Title: Capillary electrophoresis of biologically important compounds: Optimization of separation conditions by the overlapping resolution mapping scheme
Authors: Ng, C.L.
Toh, Y.L.
Li, S.F.Y. 
Lee, H.K. 
Issue Date: 1993
Source: Ng, C.L.,Toh, Y.L.,Li, S.F.Y.,Lee, H.K. (1993). Capillary electrophoresis of biologically important compounds: Optimization of separation conditions by the overlapping resolution mapping scheme. Journal of Liquid Chromatography 16 (17) : 3653-3666. ScholarBank@NUS Repository.
Abstract: The use of a simple and rapid systematic optimization scheme is described. This scheme, known as the overlapping resolution mapping scheme (ORM), makes use of nine preliminary experiments to predict the optimum separation conditions. In this investigation, the validity of the ORM scheme is verified by choosing the optimum separation conditions predicted by the scheme in the separation of a group of twelve amino acids derivatised with the N-t-butoxycarbonyl functional group, and a group of seven anti-malarial drugs. The effect of the buffer composition on the separation is also discussed.
Source Title: Journal of Liquid Chromatography
URI: http://scholarbank.nus.edu.sg/handle/10635/75688
ISSN: 01483919
Appears in Collections:Staff Publications

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