Please use this identifier to cite or link to this item: https://doi.org/10.1039/c0nr00458h
Title: Biocompatible glutathione capped gold clusters as one- and two-photon excitation fluorescence contrast agents for live cells imaging
Authors: Polavarapu, L. 
Manna, M.
Xu, Q.-H. 
Issue Date: Feb-2011
Citation: Polavarapu, L., Manna, M., Xu, Q.-H. (2011-02). Biocompatible glutathione capped gold clusters as one- and two-photon excitation fluorescence contrast agents for live cells imaging. Nanoscale 3 (2) : 429-434. ScholarBank@NUS Repository. https://doi.org/10.1039/c0nr00458h
Abstract: The one- and two-photon excitation emission properties of water soluble glutathione monolayer protected gold clusters were investigated. Strong two-photon emission was observed from the gold clusters. The two-photon absorption cross section of these gold clusters in water was deduced from the z-scan measurement to be 189740 GM, which is much higher compared to organic fluorescent dyes and quantum dots. These gold clusters also showed high photo-stability. The MTT assay showed that these gold clusters have low toxicity even at high concentrations. We have successfully demonstrated their applications for both one and two-photon excitation live cell imaging. The exceptional properties of these gold clusters make them a promising alternative for one- and two-photon bio-imaging and other nonlinear optical applications. © 2011 The Royal Society of Chemistry.
Source Title: Nanoscale
URI: http://scholarbank.nus.edu.sg/handle/10635/75664
ISSN: 20403364
DOI: 10.1039/c0nr00458h
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