Please use this identifier to cite or link to this item:
|Title:||An unnatural amino acid that mimics phosphotyrosine|
|Source:||Ge, J., Wu, H., Yao, S.Q. (2010). An unnatural amino acid that mimics phosphotyrosine. Chemical Communications 46 (17) : 2980-2982. ScholarBank@NUS Repository. https://doi.org/10.1039/c000283f|
|Abstract:||By replacing the phosphate group in pTyr with an isoxazole carboxylic acid, a novel unnatural amino acid has been successfully synthesized. Subsequently, its incorporation into a known PPI (protein-protein interaction) inhibitor of STAT3 protein (ISS 610) generated I2 which showed reasonable anti-STAT3 activity in both fluorescence polarization and cell-proliferation experiments. © The Royal Society of Chemistry 2010.|
|Source Title:||Chemical Communications|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 13, 2018
WEB OF SCIENCETM
checked on Jan 10, 2018
checked on Feb 18, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.