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|Title:||Activity-based fluorescent probes that target phosphatases|
|Authors:||Zhu, Q. |
|Citation:||Zhu, Q., Huang, X., Chen, G.Y.J., Yao, S.Q. (2003-03-24). Activity-based fluorescent probes that target phosphatases. Tetrahedron Letters 44 (13) : 2669-2672. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(03)00348-4|
|Abstract:||We have successfully designed and synthesized two fluorescently-labeled, activity-based probes, Probe 1 and Probe 2, which were shown to label protein tyrosine phosphatases specifically, as well as other types of phosphatases. The probes were not reactive towards the other non-phosphatase enzymes tested. These probes may find potential applications in large-scale proteomic experiments whereby subclasses of proteins may be selectively identified. © 2003 Elsevier Science Ltd. All rights reserved.|
|Source Title:||Tetrahedron Letters|
|Appears in Collections:||Staff Publications|
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