Please use this identifier to cite or link to this item: https://doi.org/10.1021/np970293i
Title: A new antiplatelet diarylheptanoid from Alpinia blepharocalyx
Authors: Dong, H. 
Chen, S.-X. 
Xu, H.-X. 
Kadota, S.
Namba, T.
Issue Date: 1998
Citation: Dong, H., Chen, S.-X., Xu, H.-X., Kadota, S., Namba, T. (1998). A new antiplatelet diarylheptanoid from Alpinia blepharocalyx. Journal of Natural Products 61 (1) : 142-144. ScholarBank@NUS Repository. https://doi.org/10.1021/np970293i
Abstract: A new diarylheptanoid, 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien- 5-one (1), along with seven other known compounds, were isolated from the seeds of Alpinia blepharocalyx. Of these, compounds 1 and 3 showed strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. Compound 3 also strongly inhibited ristocetin-induced platelet aggregation. Structures of these compounds were elucidated by spectroscopic and chemical means.
Source Title: Journal of Natural Products
URI: http://scholarbank.nus.edu.sg/handle/10635/75447
ISSN: 01633864
DOI: 10.1021/np970293i
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