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|Title:||A new antiplatelet diarylheptanoid from Alpinia blepharocalyx|
|Authors:||Dong, H. |
|Source:||Dong, H., Chen, S.-X., Xu, H.-X., Kadota, S., Namba, T. (1998). A new antiplatelet diarylheptanoid from Alpinia blepharocalyx. Journal of Natural Products 61 (1) : 142-144. ScholarBank@NUS Repository. https://doi.org/10.1021/np970293i|
|Abstract:||A new diarylheptanoid, 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien- 5-one (1), along with seven other known compounds, were isolated from the seeds of Alpinia blepharocalyx. Of these, compounds 1 and 3 showed strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. Compound 3 also strongly inhibited ristocetin-induced platelet aggregation. Structures of these compounds were elucidated by spectroscopic and chemical means.|
|Source Title:||Journal of Natural Products|
|Appears in Collections:||Staff Publications|
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