1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) catalyzed Michael reactions
Ye, W. Xu, J. Tan, C.-T. Tan, C.-H.
Ye, W.
Xu, J.
Tan, C.-T.
Citations
Altmetric:
Alternative Title
Abstract
1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD), a bicyclic guanidine base, has been found to be an excellent catalyst for Michael and Michael-type reactions. A wide variety of Michael donors and acceptors can participate in these reactions using 10-20 mol % of TDB. These reactions are mild, fast, easy to perform, produce excellent yields and can occur in several solvents without the need for strictly anhydrous conditions. © 2005 Elsevier Ltd. All rights reserved.
Keywords
Michael reaction, Organobase, TBD
Source Title
Tetrahedron Letters
Publisher
Series/Report No.
Collections
Rights
Date
2005-10-03
DOI
10.1016/j.tetlet.2005.08.010
Type
Article