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|Title:||Self-aggregation and thermo-responsive properties of biodegradable poly(ethylene glycol)-poly(L-lactide) amphiphilic diblock copolymers|
|Citation:||Jongpaiboonkit, L.,Zhou, Z.,Ni, X.,Li, J. (2004). Self-aggregation and thermo-responsive properties of biodegradable poly(ethylene glycol)-poly(L-lactide) amphiphilic diblock copolymers. Transactions - 7th World Biomaterials Congress : 1034-. ScholarBank@NUS Repository.|
|Abstract:||The self-aggregation properties such as micelle formation, size and shape of the micelle in aqueous environment and the thermal properties of poly(ethylene glycol) (PEG) and poly(L-lactide) (PLLA) micelles at different chain length of the hydrophobic PLLA block were investigated. The relationship of the chemical structure with the self-aggregation properties of these copolymers was also discussed. The dye absorption technique by means of fluorescence spectrophotometry using pyrene as a probe was used to observe critical micelle concentration (CMC) and micelle thermo-responsive for PEG-PLLA copolymer. The results show that an increase in molecular weight of the hydrophobic block decreases the CMC.|
|Source Title:||Transactions - 7th World Biomaterials Congress|
|Appears in Collections:||Staff Publications|
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