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|Title:||High contrast coherent anti-Stokes Raman scattering microscopy using tightly focused cylindrical vector beams|
Coherent anti-stokes raman scattering microscopy
Signal to background ratio
|Citation:||Lin, J., Lu, F., Zheng, W., Huang, Z. (2011). High contrast coherent anti-Stokes Raman scattering microscopy using tightly focused cylindrical vector beams. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 7903 : -. ScholarBank@NUS Repository. https://doi.org/10.1117/12.873674|
|Abstract:||We report on a unique annular aperture detection scheme in radially and linearly polarized coherent anti-Stokes Raman scattering (RP- and LP-CARS) microscopy to effectively remove the solvent background for high contrast vibrational imaging. Our finite-difference time-domain (FDTD) calculations show that the far-field CARS radiation from the scatterer with size comparable to the excitation wavelength is stronger than that from the solvent at large cone angles (from 45° to the maximum collection angle of the objective). The annular detection provides about one to two orders higher contrast for forward detected RP- and LP-CARS microscopy. © 2011 SPIE.|
|Source Title:||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Appears in Collections:||Staff Publications|
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