Please use this identifier to cite or link to this item: https://doi.org/10.1117/12.762177
Title: Evaluation of a fiber probe coupled with half ball lens for depth-resolved fluorescence measurements
Authors: Jaillon, F. 
Zheng, W. 
Huang, Z. 
Keywords: Beveled fiber
Epithelial tissue
Fluorescence spectroscopy
Half ball lens
Monte Carlo simulations
Issue Date: 2008
Source: Jaillon, F., Zheng, W., Huang, Z. (2008). Evaluation of a fiber probe coupled with half ball lens for depth-resolved fluorescence measurements. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6849 : -. ScholarBank@NUS Repository. https://doi.org/10.1117/12.762177
Abstract: The association of a beveled collection fiber with a half ball lens is here simulated in order to illustrate the enhancement brought by this simple method in depth resolved measurements, the latter being of major importance in the study of epithelial tissues. Indeed, in order to follow the carcinogenesis stage by a non invasive technique such as fluorescence or Raman spectroscopy, it is valuable to be able to discriminate the depth origin of the detected signal. The proposed probe design consists in a beveled collection fiber positioned on the center of the half ball lens flat surface with an off-axis excitation flat fiber. Depending on the bevel angle of the collection fiber, discrimination between the epithelial and the stromal layer can be realized.
Source Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
URI: http://scholarbank.nus.edu.sg/handle/10635/74858
ISBN: 9780819470249
ISSN: 16057422
DOI: 10.1117/12.762177
Appears in Collections:Staff Publications

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