Please use this identifier to cite or link to this item: https://doi.org/10.1117/12.760675
Title: Dynamic focusing with radial gratings for in vivo high resolution imaging
Authors: Liu, L.
Chen, N. 
Keywords: Depth-of-focus
Dynamic focusing
Optical coherence microscopy
Radial grating
Issue Date: 2008
Source: Liu, L., Chen, N. (2008). Dynamic focusing with radial gratings for in vivo high resolution imaging. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6847 : -. ScholarBank@NUS Repository. https://doi.org/10.1117/12.760675
Abstract: We propose a novel focusing scheme to achieve approximately depth-invariant lateral resolution and signal to noise ratio along an extended axial scanning range for in vivo high-resolution imaging. The pupil function of the objective lens is modulated with a series of radial gratings implemented with a spatial light modulator. Each grating gives rise to a parabolic phase aberration that shifts the focal volume with a pre-defined distance along the optical axis. Dynamic focusing is readily achieved without mechanical translation of sample or focusing optics. With spatial light modulator of higher respond time, images acquired with different focal positions can be fused to retrieve a high-resolution image with depth-invariable lateral resolution and signal to noise ratio.
Source Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
URI: http://scholarbank.nus.edu.sg/handle/10635/74852
ISBN: 9780819470225
ISSN: 16057422
DOI: 10.1117/12.760675
Appears in Collections:Staff Publications

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