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|Title:||Coherent anti-stokes raman scattering (RP-CARS) microscopy for sensing molecular orientations|
|Authors:||Fake, L. |
|Source:||Fake, L.,Jian, L.,Wei, Z.,Zhiwei, H. (2009). Coherent anti-stokes raman scattering (RP-CARS) microscopy for sensing molecular orientations. Proceedings of SPIE - The International Society for Optical Engineering 7634 : -. ScholarBank@NUS Repository. https://doi.org/10.1117/12.854965|
|Abstract:||We report coherent anti-Stokes Raman scattering (CARS) microscopy with radially polarized (RP) excitation for facilitating longitudinally oriented molecules detection. Our finite-difference time-domain (FDTD) simulation results show that the maximum near-field RP-CARS radiation from the two longitudinally orientated nanoparticles is around 1.3 times higher than that from transversely orientated nanoparticles. Our further CARS experiments show that RP-CARS radiation from molecules oriented along the longitudinal direction is approximately 3-fold stronger than that using linearly polarized CARS technique, and the lateral resolution of RP-CARS imaging can be improved by about 10% compared to the linearly polarized CARS imaging. © 2009 SPIE-OSA-IEEE.|
|Source Title:||Proceedings of SPIE - The International Society for Optical Engineering|
|Appears in Collections:||Staff Publications|
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