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Title: Autofluorescence spectroscopic imaging for laryngeal cancer detection
Authors: Kan, L. 
Zheng, W. 
Huang, Z. 
Keywords: Autofluorescence spectroscopy and imaging
Cancer detection
Optical diagnosis
Issue Date: 2008
Source: Kan, L., Zheng, W., Huang, Z. (2008). Autofluorescence spectroscopic imaging for laryngeal cancer detection. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6848 : -. ScholarBank@NUS Repository.
Abstract: Autofluorescence imaging has shown a high sensitivity for early diagnosis and detection of cancer and precancer in humans, however, this diagnostic technique has a limitation with high false positive rates resulting in a low diagnostic specificity. In this study, we develop an endoscope-based autofluorescence imaging system in combination with spectroscopy measurement system for tissue diagnostics and characterization in the head and neck. The results show that combining the spectroscopy and imaging techniques can improve both the diagnostic sensitivity and specificity for discriminating laryngeal carcinoma from normal tissue.
Source Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
ISBN: 9780819470232
ISSN: 16057422
DOI: 10.1117/12.762249
Appears in Collections:Staff Publications

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