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|Title:||Annular aperture detection scheme in radially polarized coherent anti-Stokes Raman scattering (RP-CARS) microscopy for contrast improvement|
Coherent anti-Stokes Raman scattering microscopy
Signal to background ratio
|Source:||Lin, J., Lu, F., Wang, H., Zheng, W., Sheppard, C.J.R., Huang, Z. (2010). Annular aperture detection scheme in radially polarized coherent anti-Stokes Raman scattering (RP-CARS) microscopy for contrast improvement. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 7569 : -. ScholarBank@NUS Repository. https://doi.org/10.1117/12.842942|
|Abstract:||We report on a unique annular aperture detection scheme in radially polarized coherent anti-Stokes Raman scattering (RP-CARS) microscopy to effectively remove the solvent background for high contrast vibrational imaging. Our finite-difference time-domain (FDTD) calculations show that the far-field RP-CARS radiation from the scatterer with size comparable to the excitation wavelength is stronger than that from the solvent at large cone angles (around 45° to 150°). The annular detection provides about one order higher contrast for both forward and backward detected RP-CARS microscopy. © 2010 Copyright SPIE - The International Society for Optical Engineering.|
|Source Title:||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Appears in Collections:||Staff Publications|
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