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|Title:||Stirring immiscible liquids in nanoliter cavities|
|Keywords:||Aqueous two-phase systems|
|Source:||Lee, S.H.S.,Wang, P.,Yap, S.K.,Khan, S.A. (2011). Stirring immiscible liquids in nanoliter cavities. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 1 : 677-679. ScholarBank@NUS Repository.|
|Abstract:||In this paper, we present immiscible liquid mixing within nanoliter droplet-based 'cavities' in microfluidic devices. In doing so, we create biphasic droplets with tunable internal structures, from near-equilibrium drop-in-drop morphologies to complex yet uniform non-equilibrium steady-state structures. The droplets contain an aqueous mixture of poly(ethylene glycol) (PEG) and dextran (DEX), and are injected into an immiscible oil in a simple microfluidic T-junction device. Aqueous droplets with tunable spatial heterogeneity in structure and composition could potentially be used to conduct in vitro biochemistry in environments that more closely emulate in vivo milieus than conventional macro or micro methods. Copyright © (2011) by the Chemical and Biological Microsystems Society.|
|Source Title:||15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011|
|Appears in Collections:||Staff Publications|
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