Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/74760
Title: Stirring immiscible liquids in nanoliter cavities
Authors: Lee, S.H.S.
Wang, P.
Yap, S.K.
Khan, S.A. 
Keywords: Aqueous two-phase systems
Biomolecular separation
Chaotic advection
Droplet microfluidics
Mixing
Issue Date: 2011
Source: Lee, S.H.S.,Wang, P.,Yap, S.K.,Khan, S.A. (2011). Stirring immiscible liquids in nanoliter cavities. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 1 : 677-679. ScholarBank@NUS Repository.
Abstract: In this paper, we present immiscible liquid mixing within nanoliter droplet-based 'cavities' in microfluidic devices. In doing so, we create biphasic droplets with tunable internal structures, from near-equilibrium drop-in-drop morphologies to complex yet uniform non-equilibrium steady-state structures. The droplets contain an aqueous mixture of poly(ethylene glycol) (PEG) and dextran (DEX), and are injected into an immiscible oil in a simple microfluidic T-junction device. Aqueous droplets with tunable spatial heterogeneity in structure and composition could potentially be used to conduct in vitro biochemistry in environments that more closely emulate in vivo milieus than conventional macro or micro methods. Copyright © (2011) by the Chemical and Biological Microsystems Society.
Source Title: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
URI: http://scholarbank.nus.edu.sg/handle/10635/74760
ISBN: 9781618395955
Appears in Collections:Staff Publications

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