Please use this identifier to cite or link to this item:
|Title:||Designing biological apatite suitable for neomycin delivery|
|Authors:||Murugan, R. |
|Source:||Murugan, R., Ramakrishna, S. (2006-07). Designing biological apatite suitable for neomycin delivery. Journal of Materials Science 41 (13) : 4343-4347. ScholarBank@NUS Repository. https://doi.org/10.1007/s10853-006-6157-z|
|Abstract:||Bovine-derived biological apatite has a long history for use in human health care as bone substitute. This article reports an elegant method of designing bovine-derived hydroxyapatite (BHA) blocks suitable for drug delivery. Neomycin sulphate (NS) was selected as a model drug and its loading and release studies were performed under in-vitro physiological conditions. The results indicate that phase purity and structural integrity of the BHA are retained even after entrapment of drug molecules. It was noticed that the rate of neomycin delivery was directly proportional to the porosity of the BHA blocks. The in-vitro release studies suggest that BHA may be used as a good carrier system for neomycin delivery. © 2006 Springer Science + Business Media, Inc.|
|Source Title:||Journal of Materials Science|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 13, 2018
WEB OF SCIENCETM
checked on Feb 19, 2018
checked on Feb 18, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.