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Title: Regenerative medicine: Implications for craniofacial surgery
Authors: Schantz, J.-T.
MacHens, H.-G.
Schilling, A.F.
Teoh, S.-H. 
Keywords: biocomposite engineering
Craniofacial reconstruction
mesenchyme-derived tissues
neural crestYderived tissues
tissue engineering
Issue Date: Mar-2012
Citation: Schantz, J.-T., MacHens, H.-G., Schilling, A.F., Teoh, S.-H. (2012-03). Regenerative medicine: Implications for craniofacial surgery. Journal of Craniofacial Surgery 23 (2) : 530-536. ScholarBank@NUS Repository.
Abstract: Craniofacial reconstruction of cases with complex anatomy challenges surgeons. The recently emerging field of tissue engineering and regenerative medicine has resulted in a variety of novel therapeutic concepts particularly in the craniofacial area. However, researchers still face significant problems when translating scientific concepts from the bench to the bedside. Reconstruction procedures depend on sustainability, aesthetic outcome, and functionality. Tissue engineering approaches yield powerful tools for long-term satisfying results enabling customized reconstruction and supporting natural healing processes. In conclusion, further advances of tissue-engineered reconstruction need multidisciplinary research to create complex tissue structures and make satisfactory outcomes clinically achievable for most patients. This review highlights clinical advances in the field and gives an overview about current scientific concepts. Copyright © 2012 by Mutaz B. Habal, MD.
Source Title: Journal of Craniofacial Surgery
ISSN: 10492275
DOI: 10.1097/SCS.0b013e318241dc3a
Appears in Collections:Staff Publications

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