Please use this identifier to cite or link to this item: https://doi.org/10.1007/s11517-010-0611-4
Title: Microfluidics for cell separation
Authors: Bhagat, A.A.S.
Bow, H.
Hou, H.W.
Tan, S.J.
Han, J.
Lim, C.T. 
Issue Date: Oct-2010
Source: Bhagat, A.A.S., Bow, H., Hou, H.W., Tan, S.J., Han, J., Lim, C.T. (2010-10). Microfluidics for cell separation. Medical and Biological Engineering and Computing 48 (10) : 999-1014. ScholarBank@NUS Repository. https://doi.org/10.1007/s11517-010-0611-4
Abstract: The need for efficient cell separation, an essential preparatory step in many biological and medical assays, has led to the recent development of numerous microscale separation techniques. This review describes the current state-of-the-art in microfluidics-based cell separation techniques. Microfluidics-based sorting offers numerous advantages, including reducing sample volumes, faster sample processing, high sensitivity and spatial resolution, low device cost, and increased portability. The techniques presented are broadly classified as being active or passive depending on the operating principles. The various separation principles are explained in detail along with popular examples demonstrating their application toward cell separation. Common separation metrics, including separation markers, resolution, efficiency, and throughput, of these techniques are discussed. Developing efficient microscale separation methods that offering greater control over cell population distribution will be important in realizing true point-of-care (POC) lab-on-a-chip (LOC) systems. © 2010 International Federation for Medical and Biological Engineering.
Source Title: Medical and Biological Engineering and Computing
URI: http://scholarbank.nus.edu.sg/handle/10635/68307
ISSN: 01400118
DOI: 10.1007/s11517-010-0611-4
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

224
checked on Dec 7, 2017

WEB OF SCIENCETM
Citations

215
checked on Nov 29, 2017

Page view(s)

26
checked on Dec 11, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.