Please use this identifier to cite or link to this item: https://doi.org/10.1002/mame.201200323
Title: Green processing of nanofibers for regenerative medicine
Authors: Krishnan, R.
Sundarrajan, S. 
Ramakrishna, S. 
Keywords: aqueous electrospinning
biopolymers
polymer nanofibers
polysaccharides
regenerative medicine
Issue Date: Oct-2013
Source: Krishnan, R., Sundarrajan, S., Ramakrishna, S. (2013-10). Green processing of nanofibers for regenerative medicine. Macromolecular Materials and Engineering 298 (10) : 1034-1058. ScholarBank@NUS Repository. https://doi.org/10.1002/mame.201200323
Abstract: Electrospinning of polymer scaffolds is mostly carried out using organic solvents, but the drawbacks are: solvent costs, environmental hazards, and presence of traces of solvent impurities. The use of water-soluble polymers (WSPs), water or aqueous solutions as an electrospinning medium (green processing) is a very attractive method to avoid such issues. However, a few WSP such as polyelectrolytes are not spinnable as such, but have been electrospun by addition of WSPs, additives, and salts. This paper covers solution properties, polyelectrolyte nanofibrous scaffolds (polysaccharides, biopolymers, etc.), fabrication through green processing, and their regenerative medical applications such as wound dressing, drug delivery, and tissue engineering. This is the first review to cover the above issues, the drawbacks of current methods, and future challenges. The fabrication of polyelectrolyte nanofiber scaffolds from aqueous polymer solution via a green electrospinning process is described. Generation of different architectures under various spinning conditions, application of polysaccharides and biopolymers scaffolds (for skin, cartilage, heart, and bone applications), drawbacks of the current methods, and future challenges are reviewed. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Macromolecular Materials and Engineering
URI: http://scholarbank.nus.edu.sg/handle/10635/68264
ISSN: 14387492
DOI: 10.1002/mame.201200323
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

14
checked on Feb 15, 2018

WEB OF SCIENCETM
Citations

13
checked on Feb 5, 2018

Page view(s)

39
checked on Feb 13, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.