Please use this identifier to cite or link to this item: https://doi.org/10.1002/biot.201200249
Title: Electrospun synthetic and natural nanofibers for regenerative medicine and stem cells
Authors: Kai, D.
Jin, G.
Prabhakaran, M.P. 
Ramakrishna, S. 
Keywords: Cell infiltration
Electrospinning
Nanofibers
Stem cell differentiation
Tissue engineering
Issue Date: Jan-2013
Source: Kai, D., Jin, G., Prabhakaran, M.P., Ramakrishna, S. (2013-01). Electrospun synthetic and natural nanofibers for regenerative medicine and stem cells. Biotechnology Journal 8 (1) : 59-72. ScholarBank@NUS Repository. https://doi.org/10.1002/biot.201200249
Abstract: Nanofibers are attractive substrates for tissue regeneration applications because they structurally mimic the native extracellular matrix. Electrospinning has been recognized as one of the most efficient techniques to fabricate polymer nanofibers. Recent research has demonstrated that cellular responses, for example attachment, proliferation and differentiation, can be modulated by tuning nanofiber properties. In combination with other processing techniques, such as particulate leaching or three-dimensional printing, nanofibrous scaffolds incorporating macroporous networks could be developed to enhance infiltration of cells. Three dimensional nanofiber-based constructs offer an opportunity to achieve advanced functional tissue regeneration. This review explores the advantageous effects of nanofibers on cell behaviors compared to traditional scaffolds. © 2013.
Source Title: Biotechnology Journal
URI: http://scholarbank.nus.edu.sg/handle/10635/68222
ISSN: 18606768
DOI: 10.1002/biot.201200249
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