Please use this identifier to cite or link to this item: https://doi.org/10.1517/13543776.17.8.965
Title: Biodegradable thermosensitive copolymer hydrogels for drug delivery
Authors: Loh, X.J.
Li, J. 
Keywords: Biodegradable
Block copolymer
Drug delivery
Hydrogel
Thermosensitive
Issue Date: Aug-2007
Source: Loh, X.J., Li, J. (2007-08). Biodegradable thermosensitive copolymer hydrogels for drug delivery. Expert Opinion on Therapeutic Patents 17 (8) : 965-977. ScholarBank@NUS Repository. https://doi.org/10.1517/13543776.17.8.965
Abstract: Biodegradable thermogelling copolymer hydrogels have great applicative potential in areas such as sustained drug release, gene delivery and tissue engineering. These injectable materials can be implanted in the human body with minimal surgical intervention. The thermosensitive copolymers have been incorporated with a variety of biocompatible and biodegradable components such as poly(D,L-lactic acid-co-glycolic acid), poly(L-lactic acid), poly (L-carprolactone), poly([R]-3-hydroxybutyrate), poly(organophosphazene), poly(peptide), poly(propylene fumarate), poly(propylene phosphate), polyacetal and poly(ortho ester). Various formulations consisting of the copolymers and therapeutic agents have been developed and the sustained release of these agents has been demonstrated. This review aims to provide a comprehensive summary of the recent developments in this field of study and highlights the most recent intellectual property and research papers. © 2007 Informa UK Ltd.
Source Title: Expert Opinion on Therapeutic Patents
URI: http://scholarbank.nus.edu.sg/handle/10635/68142
ISSN: 13543776
DOI: 10.1517/13543776.17.8.965
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