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|Title:||Miniaturized platforms for the detection of single-nucleotide polymorphisms|
Single-nucleotide polymorphisms (SNPs)
|Source:||Ng, J.K.-K., Liu, W.-T. (2006-10). Miniaturized platforms for the detection of single-nucleotide polymorphisms. Analytical and Bioanalytical Chemistry 386 (3) : 427-434. ScholarBank@NUS Repository. https://doi.org/10.1007/s00216-006-0552-9|
|Abstract:||Conventional methods for detecting single-nucleotide polymorphisms (SNPs), the most common form of genetic variation in human beings, are mostly limited by their analysis time and throughputs. In contrast, advances in microfabrication technology have led to the development of miniaturized platforms that can potentially provide rapid high-throughput analysis at small sample volumes. This review highlights some of the recent developments in the miniaturization of SNP detection platforms, including microarray-based, bead-based microfluidic and microelectrophoresis-based platforms. Particular attention is paid to their ease of fabrication, analysis time, and level of throughput. © Springer-Verlag 2006.|
|Source Title:||Analytical and Bioanalytical Chemistry|
|Appears in Collections:||Staff Publications|
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