Please use this identifier to cite or link to this item: https://doi.org/10.1063/1.3665936
Title: Two-photon focal modulation microscopy in turbid media
Authors: Si, K.
Gong, W. 
Chen, N. 
Sheppard, C.J.R. 
Issue Date: 5-Dec-2011
Source: Si, K., Gong, W., Chen, N., Sheppard, C.J.R. (2011-12-05). Two-photon focal modulation microscopy in turbid media. Applied Physics Letters 99 (23) : -. ScholarBank@NUS Repository. https://doi.org/10.1063/1.3665936
Abstract: The image formation of two-photon focal modulation microscopy (2PFMM) in turbid media is theoretically investigated. The results show that compared with conventional two-photon fluorescence microscopy, the ballistic excitation of 2PFMM is concentrated in a much smaller region around the focal point and decays more rapidly outside the focal volume, while the scattered excitation is largely suppressed. When focuses at 1600 μm, the signal-to-background ratio and signal-to-noise ratio of 2PFMM are improved by 30 dB and 18 dB, respectively, indicating that 2PFMM can achieve a large imaging penetration depth. © 2011 American Institute of Physics.
Source Title: Applied Physics Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/67338
ISSN: 00036951
DOI: 10.1063/1.3665936
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