Please use this identifier to cite or link to this item: https://doi.org/10.1021/nl402719q
Title: Nanomechanics insights into the performance of healthy and osteoporotic bones
Authors: Wang, Y.-T.
Chang, S.-Y.
Huang, Y.-C.
Tsai, T.-C.
Chen, C.-M.
Lim, C.T. 
Keywords: Bone
fracture
in situ TEM indentation
nanomechanics
osteoporosis
Issue Date: 13-Nov-2013
Citation: Wang, Y.-T., Chang, S.-Y., Huang, Y.-C., Tsai, T.-C., Chen, C.-M., Lim, C.T. (2013-11-13). Nanomechanics insights into the performance of healthy and osteoporotic bones. Nano Letters 13 (11) : 5247-5254. ScholarBank@NUS Repository. https://doi.org/10.1021/nl402719q
Abstract: In situ nanoscopic observations of healthy and osteoporotic bone nanopillars under compression were performed. The structural-mechanical property relationship at the atomic scale suggests that cortical bone performance is correlated to the feature, arrangement, movement, distortion, and fracture of hydroxyapatite nanocrystals. Healthy bone comprising tightly bound mineral nanocrystals shows high structural stability with nanoscopic lattice distortions and dislocation activities. On the other hand, osteoporotic bone exhibits brittleness owing to the movements of dispersed minerals in and intergranular fracture along a weak organic matrix. © 2013 American Chemical Society.
Source Title: Nano Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/67183
ISSN: 15306984
DOI: 10.1021/nl402719q
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