Please use this identifier to cite or link to this item:
|Title:||Multi-contrast focal modulation microscopy for in vivo imaging of thick biological tissues|
|Authors:||Chen, N. |
|Citation:||Chen, N., Gao, G. (2012-05-21). Multi-contrast focal modulation microscopy for in vivo imaging of thick biological tissues. Optics Express 20 (11) : 12166-12170. ScholarBank@NUS Repository. https://doi.org/10.1364/OE.20.012166|
|Abstract:||In vivo high resolution imaging of biological tissues is desirable for a wide range of biomedical applications. Recently focal modulation microscopy (FMM) has been developed and an imaging depth comparable to multi-photon microscopy (MPM) and optical coherence microscopy (OCM) has been achieved. Here we report the first focal modulation microscope that is capable of performing real-time fluorescence and scattering imaging simultaneously on thick biological tissues. A novel spatiotemporal phase modulator (STPM) has been designed and integrated into such a microscope to achieve high performances in terms of imaging speed, contrast, effective spatial resolution, signal to noise ratio, and compatibility with multiple excitation wavelengths. © 2012 Optical Society of America.|
|Source Title:||Optics Express|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Sep 24, 2018
WEB OF SCIENCETM
checked on Sep 17, 2018
checked on Aug 17, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.