Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.colsurfb.2005.11.006
Title: Micropatterning of polystyrene nanoparticles and its bioapplications
Authors: Wang, C. 
Yap, F.L.
Zhang, Y. 
Keywords: Micropatterning: Antibody microarray
Polystyrene nanoparticle
Issue Date: 30-Dec-2005
Source: Wang, C., Yap, F.L., Zhang, Y. (2005-12-30). Micropatterning of polystyrene nanoparticles and its bioapplications. Colloids and Surfaces B: Biointerfaces 46 (4) : 255-260. ScholarBank@NUS Repository. https://doi.org/10.1016/j.colsurfb.2005.11.006
Abstract: Micropatterning of biomolecules forms the basis of cell culture, biosensor and microarray technology. Currently, the most widely used techniques are photoresist lithography, soft lithography or using robots which all involve multi-step surface modification directly on a planar substrate. Here we report a method to pattern biomolecules through self-assembling polystyrene nanoparticles in arrayed microwells on a solid surface to form well-ordered patterning, followed by attaching biomolecules to the assembled nanoparticles. The formation of colloidal patterns depends on capillary force, surface wettability and physical confinement. This method can be used for micropatterning a variety of biomolecules such as protein and antibody. © 2005 Elsevier B.V. All rights reserved.
Source Title: Colloids and Surfaces B: Biointerfaces
URI: http://scholarbank.nus.edu.sg/handle/10635/67157
ISSN: 09277765
DOI: 10.1016/j.colsurfb.2005.11.006
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