Please use this identifier to cite or link to this item: https://doi.org/10.1117/1.3050447
Title: Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment
Authors: Yuen, C. 
Zheng, W. 
Huang, Z. 
Keywords: Polystyrene bead
Raman spectroscopy
Saliva
Surface-enhanced Raman scattering
Issue Date: 2008
Source: Yuen, C., Zheng, W., Huang, Z. (2008). Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment. Journal of Biomedical Optics 13 (6) : -. ScholarBank@NUS Repository. https://doi.org/10.1117/1.3050447
Abstract: We report a novel postgrowth microwave heating implementation by selectively modifying hierarchical polystyrene (PS) bead substrates coated with gold (Au) films to effectively improve the surface-enhanced Raman scattering (SERS) effect on the analytes. The SERS signal of probe molecule rhodamine 6G (Rh 6G) on the microwave-treated Au-PS substrates can be improved by 10-fold, while the detection limit of Rh 6G in concentration can be enhanced by two orders of magnitude compared to the as-growth substrates. The high-quality SERS spectrum of saliva can also be acquired using the modified substrates, demonstrating the potential for the realization of the high-performance SERS substrates for biomedical applications. © 2008 Society of Photo-Optical Instrumentation Engineers.
Source Title: Journal of Biomedical Optics
URI: http://scholarbank.nus.edu.sg/handle/10635/67101
ISSN: 10833668
DOI: 10.1117/1.3050447
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