Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug
Hu, Q.-D. Fan, H. Ping, Y. Liang, W.-Q. Tang, G.-P. Li, J.
Hu, Q.-D.
Fan, H.
Ping, Y.
Liang, W.-Q.
Tang, G.-P.
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Alternative Title
Abstract
Self-assembly supramolecular nanoparticles (SNPs) are synthesized using polyethylenimine (PEI) crosslinked by cyclodextrins (CyDs), adamantyl doxorubicin and plasmid DNA. SNPs successfully conduct the cooperative co-delivery of chemotherapeutic anticancer drug and plasmid DNA in vitro and in vivo. © 2011 The Royal Society of Chemistry.
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Source Title
Chemical Communications
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Date
2011-05-21
DOI
10.1039/c1cc10721f
Type
Article