Please use this identifier to cite or link to this item: https://doi.org/4/008
Title: Beveled fiber-optic probe couples a ball lens for improving depth-resolved fluorescence measurements of layered tissue: Monte Carlo simulations
Authors: Jaillon, F. 
Zheng, W. 
Huang, Z. 
Issue Date: 2008
Source: Jaillon, F.,Zheng, W.,Huang, Z. (2008). Beveled fiber-optic probe couples a ball lens for improving depth-resolved fluorescence measurements of layered tissue: Monte Carlo simulations. Physics in Medicine and Biology 53 (4) : 937-951. ScholarBank@NUS Repository. https://doi.org/4/008
Abstract: In this study, we evaluate the feasibility of designing a beveled fiber-optic probe coupled with a ball lens for improving depth-resolved fluorescence measurements of epithelial tissue using Monte Carlo (MC) simulations. The results show that by using the probe configuration with a beveled tip collection fiber and a flat tip excitation fiber associated with a ball lens, discrimination of fluorescence signals generated in different tissue depths is achievable. In comparison with a flat-tip collection fiber, the use of a large bevel angled collection fiber enables a better differentiation between the shallow and deep tissue layers by changing the excitation-collection fiber separations. This work suggests that the beveled fiber-optic probe coupled with a ball lens has the potential to facilitate depth-resolved fluorescence measurements of epithelial tissues. © 2008 Institute of Physics and Engineering in Medicine.
Source Title: Physics in Medicine and Biology
URI: http://scholarbank.nus.edu.sg/handle/10635/66942
ISSN: 00319155
DOI: 4/008
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